A team of highly skilled Navy SEALS find themselves embarking on the battle of their lives when they come face-to-face with the undead. After a deadly outbreak occurs in New Orleans, the SEALS must fight for their lives, and the city, against an army of zombies.

The reformed criminal Paul Maguire is a businessman in the construction business and happily married with Vanessa Maguire. His sixteen year-old daughter Caitlin Maguire is his pride and joy. One night, Paul and Vanessa go to a dinner party and leave Caitlin with her friends Mike and Evan at home. During the night, his dinner is interrupted by Detective Peter St. John that tells that Caitlin had been kidnapped and her friends are wounded. Paul learns that three criminals had invaded his house and abducted his daughter. Paul meets his friends and former crew, Kane and Danny Doherty, and they unsuccessfully press the smalltime criminals expecting to have news from Caitlin. Soon she is found dead in a park and they see the result of the ballistics indicating that a Russian Tokarev pistol killed Caitlin. Now Paul is haunted by his past and believes that the Russians are seeking revenge. Paul, Kane and Danny start a war against the Russians but no mobster knows any connection of the Russian...

In New Orleans just before Hurricane Katrina hits, a pregnant woman gives birth prematurely. She dies and her baby is in critical condition. The baby has to be kept in a ventilator. When the hurricane strikes, all the power goes out and everyone in the hospital leaves. But the baby's father stays because the baby can't be moved so he has to take care of his baby by making sure the ventilator stays on. And because there's no power, the only power source is generator that he has to crank every few minutes. So he has to stay awake while waiting for someone to come for them.

Seventeen year-old Nell Margaret Sweetzer is found completely insane when trying to explain her possession by the demon called Abalam. After medical and psychological treatment, she is sent to the Deveraux transition house in New Orleans managed by Frank Merle, who helps her to start a new life. She finds a job as a hotel housekeeper, befriends her new roommates, and develops a crush on her coworker, Chris. Soon, Nell comes to realize that she is haunted by people from her cult... and by the same evil force that once possessed her. When Nell meets Miss Cecile, she tells Nell that she has been following her since the hospital. Further, she discloses that she belongs to the sect Order of The Right Hand, and that they can protect her from the evil in an attempt to divert the prophecy of an apocalypse. Will Nell accept help, and be protected from the extremely powerful, evil force Abalam -- Or will she come to accept... herself?